Patent applications are worldwide patent applications filed through the Patent Cooperation Treaty procedure or with a national patent office.
| 1990 | 2000 | 2005 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Costa Rica | 15 | 28 | 17 | 8 | 13 | 9 | 18 | 15 | 17 | 9 | 19 | 8 | 16 | 12 | 15 |
| República Dominicana | 5 | 8 | 15 | 15 | 19 | 12 | 16 | 25 | 28 | 20 | 17 | 23 | 10 | 7 | |
| El Salvador | 10 | 7 | 4 | 4 | 3 | 1 | 4 | 2 | |||||||
| Guatemala | 27 | 54 | 17 | 7 | 4 | 7 | 4 | 10 | 7 | 3 | 3 | 6 | 7 | 7 | 9 |
| Honduras | 6 | 4 | 2 | 8 | 6 | 4 | 10 | 4 | 8 | ||||||
| Nicarágua | 14 | 2 | 4 | 3 | 1 | ||||||||||
| Panamá | 15 | 7 | 21 | 9 | 13 | 14 | 68 | 33 | 135 | 34 | 22 | 35 |