Patent applications are worldwide patent applications filed through the Patent Cooperation Treaty procedure or with a national patent office.
| 1990 | 2000 | 2005 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Argentina | 955 | 1.062 | 1.054 | 552 | 688 | 735 | 643 | 509 | 546 | 884 | 393 | 425 | 442 | 930 | 406 |
| Bolívia | 9 | 12 | 59 | 8 | 5 | ||||||||||
| Brasil | 2.389 | 3.179 | 4.054 | 4.228 | 4.695 | 4.798 | 4.959 | 4.659 | 4.641 | 5.200 | 5.480 | 4.980 | 5.464 | 5.280 | 4.666 |
| Chile | 169 | 241 | 361 | 328 | 339 | 336 | 340 | 452 | 443 | 386 | 425 | 406 | 438 | 372 | 402 |
| Colômbia | 75 | 99 | 133 | 183 | 213 | 251 | 260 | 321 | 545 | 595 | 415 | 422 | 369 | 432 | |
| Cuba | 105 | 62 | 38 | 27 | 24 | 32 | 29 | 29 | 27 | 33 | 21 | ||||
| Equador | 10 | 11 | 4 | 7 | 24 | 20 | 45 | 16 | 34 | 29 | 33 | 35 | |||
| México | 661 | 431 | 584 | 951 | 1.065 | 1.294 | 1.210 | 1.246 | 1.364 | 1.310 | 1.334 | 1.555 | 1.305 | 1.132 | 1.117 |
| Panamá | 15 | 7 | 21 | 9 | 13 | 14 | 68 | 33 | 135 | 34 | 22 | 35 | |||
| Paraguai | 16 | 11 | 24 | 18 | 34 | 4 | 14 | 10 | |||||||
| Peru | 49 | 40 | 27 | 39 | 39 | 54 | 73 | 83 | 67 | 72 | 100 | 89 | 137 | 125 | 94 |
| Uruguai | 44 | 24 | 23 | 20 | 22 | 37 | 26 | 23 | |||||||
| Venezuela (República Bolivariana da) | 262 | 56 | 121 | 70 | 61 | 65 | 74 | 55 | 47 | 35 | 96 |